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Deferasirox removes cardiac iron and attenuates oxidative stress in the iron-overloaded gerbil

โœ Scribed by Rabaa M. Al-Rousan; Satyanarayana Paturi; Joseph P. Laurino; Sunil K. Kakarla; Anil K. Gutta; Ernest M. Walker; Eric R. Blough


Book ID
101437525
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
302 KB
Volume
84
Category
Article
ISSN
0361-8609

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Gerbils administered iron dextran are the only animal species which have been shown to develop hemochromatosis of the liver and heart in the same manner as transfusion dependent homozygous thalassemics. The iron chelating hydroxypyridinone, CP94, has been administered prophylactically to iron overlo