Does phentermine inhibit monoamine oxidase?
โ Scribed by Richard B Rothman
- Book ID
- 117293826
- Publisher
- The Lancet
- Year
- 1999
- Tongue
- English
- Weight
- 62 KB
- Volume
- 353
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
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entitled: ''Phentermine, an unrecognized MAO inhibitor, probably increases free plasma serotonin when given with serotonin uptake blockers.'' Similar information was just published in a recent issue of Lancet (Maher et al.,1999). The authors assert that phentermine, an amphetamine analog and FDA-app
The nontricyclic antidepressant trazodone and the related triazolo antidepressants nefazodone and etoperidone are monoamine uptake inhibitors. We quantified the interaction of these compounds with monoamine oxidases in vitro and in vivo. All three compounds were devoid of activity in these studies.