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Does local X-irradiation of a tumor increase the incidence of metastases?

✍ Scribed by Donald Baker; David Elkon; Meng-Lai Lim; William Constable; Harold Wanebo


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
442 KB
Volume
48
Category
Article
ISSN
0008-543X

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Courses of irradiation consisting of 6000 rad in ten equal fractions over 12 days delivered to KHT sarcomas in mice controlled 55% of the local tumors but 83% of the mice died from metastases. Three strategies to reduce the risk of metastatic spread were tested. The fractionation scheme was changed