𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Does Hydroxyurea inhibit Chromosome Repair in Cultured Human Lymphocytes?

✍ Scribed by PREMPREE, T.; MERZ, T.


Book ID
109669825
Publisher
Nature Publishing Group
Year
1969
Tongue
English
Weight
230 KB
Volume
224
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The Clastogenic effect of Pyrimethamine
✍ Ü. Egeli; G. Erdogan πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 973 KB

In this study the clastogenic effect of pyrimethamine (Daraprim), a folic acid antagonist used for the treatment of toxoplasmosis and malaria on human chromosomes, was investigated. Pyrimethamine was added to in vitro lymphocyte cultures at six different concentrations: 0.05 (normal therapeutic dose

Protection and induction of chromosomal
✍ LusΓ’nia M. Greggi Antunes; Catarina S. Takahashi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 37 KB πŸ‘ 2 views

Some chemotherapeutic approaches have proposed the use of antioxidants such as vitamin C (VC) to minimize the cytotoxicity and damage induced in normal tissue by antitumor agents that produce free radicals. Nevertheless, VC can also be cytotoxic, genotoxic, and harmful when combined with antitumor a

Chromosome-damaging action of isoniazid
✍ Y. R. Ahuja; Madhuri Jaju; Manjula Jaju πŸ“‚ Article πŸ“… 1981 πŸ› Springer 🌐 English βš– 187 KB

Antitubercular drugs in general are given in various combinations, one being isoniazid and thiacetazone. In the present study, was evaluated the in vivo chromosome-damaging effects of a combination of these two drugs in 72 h lymphocyte cultures. Chromosome aberrations were significantly increased in