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Docking and Quantitative Structure–Activity Relationship Studies for the Bisphenylbenzimidazole Family of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase

✍ Scribed by Carlos F. Lagos; Julio Caballero; Fernando D. Gonzalez-Nilo; Carlos David Pessoa-Mahana; Tomas Perez-Acle


Book ID
111368597
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
652 KB
Volume
72
Category
Article
ISSN
1747-0277

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✍ Antonio Lavecchia; Roberta Costi; Marino Artico; Gaetano Miele; Ettore Novellino 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB

## Abstract Arylthio isopropyl pyridinylmethylpyrrolemethanols (AThPs) have been recently reported as a new class of human immunodeficiency virus type 1 (HIV‐1) reverse transcriptase (RT) inhibitors acting at the non‐nucleoside binding site (NNBS) of this enzyme. Docking experiments of the potent i