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Docetaxel-induced apoptosis of human umbilical vein endothelial cells (HUVECs) is mediated by the activation of MAPK and modulation in Bcl-2 family proteins

✍ Scribed by J. Kim; J. Lee; H. Kim; E. Chang


Book ID
119597991
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
6
Category
Article
ISSN
1359-6349

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## Abstract ## Background This study evaluates whether taurolidine, a novel antibiotic agent, induces murine melanoma cell apoptosis in vitro and in vivo. ## Methods Murine melanoma cells (B16 4A5 and B16 F10) were treated with taurolidine (0–100 Β΅M) for 12 and 24 hr. Cell viability and apoptosi