๐”– Bobbio Scriptorium
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Do ribosomes regulate mitochondrial RNA synthesis?

โœ Scribed by Howard T. Jacobs


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
931 KB
Volume
11
Category
Article
ISSN
0265-9247

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โœฆ Synopsis


The levels of different classes of mitochondrially encoded transcripts are decelopmentally regulated in sea urchin embryos, as a result of selection between mutually exclusive synthetic pathways. Z propose a simple model to explain these observations, based on a dual role for mitochondrial ribosomes and translation factors in RNA synthesis as well as in translation. This effect may be exerted either at the transcriptional or posttranscriptional level (or both), and is potentially generalizable to mammalian mtDNA and to other systems.


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