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Do identical HLA-DR3 genes convey susceptibility to celiac disease and insulin dependent diabetes mellitus?

โœ Scribed by C. BRAUTBAR; J. ZLOTOGORA; N. LAUFER; T. COHEN; E. D. ALBERT


Book ID
115093551
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
140 KB
Volume
23
Category
Article
ISSN
0001-2815

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In this study HLA-DQA1 and TNF genes in addition to HLA-DQB1 gene were investigated at DNA level for elucidation of the genetic backgrounds of Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. DNA, amplified by polymerase chain reaction, was subjected to allele specific oligonucleot