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Do Cytotoxic Lymphocytes Kill via Reactive Oxygen Species?

✍ Scribed by Mark S. Williams; Pierre A. Henkart


Book ID
116570428
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
45 KB
Volume
22
Category
Article
ISSN
1074-7613

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CD8 + cytotoxic lymphocytes, natural killer cells and lymphokine-activated killer cells depend primarily on the perforin/granzyme system to kill their targets, while CD4 + T cells utilize Fas and other mechanisms to induce cell death. The molecular mechanisms used by these pathways to induce target