Do CD4 or CD8 molecules provide a regulatory signal in T-cell activation?
β Scribed by Bernhard Fleischer; Hubert Schrezenmeier
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 432 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-5699
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Only small populations of nonactivated, nonproliferating Foxp3 Ψ CD4 regulatory T cell (T R ) cells are found in the nonparenchymal cell compartment of the mouse liver while liver-draining celiac nodes contain expanded, activated T R cell populations (similar to other lymph nodes). Liver Foxp3 Ψ CD4
For some membrane-associated antigens, the number of molecules expressed per cell carries information about the cell's differentiation and activation state. Quantitating antigen expression by flow cytometry has immediate application in monitoring CD38 expression on CD8 Ψ T cells in human immunodefic