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Do calcium channel autoantibodies cause cerebellar ataxia with Lambert–Eaton syndrome?

✍ Scribed by Colin F. Fletcher; Vanda A. Lennon


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
58 KB
Volume
53
Category
Article
ISSN
0364-5134

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✍ Akihito Suenaga; Susumu Shirabe; Tatsufumi Nakamura; Masakatsu Motomura; Mitsuhi 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 1 views

Lambert-Eaton myasthenic syndrome (LEMS) is a neurological disorder characterized by reduced presynaptic release of acetylcholine.' Antibodies measured with o-conotoxin GVIA (GVIA), a long-lasting N-type calcium channel blocker, have been detected in 44-90% of patients with LEMS and in 10-42% of pat