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DNA tracking within a nanochannel: device fabrication and experiments

✍ Scribed by Mokkapati, V. R. S. S.; Di Virgilio, V.; Shen, C.; Mollinger, J.; Bastemeijer, J.; Bossche, A.

Book ID
120558083
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
474 KB
Volume
11
Category
Article
ISSN
1473-0197

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## Abstract Supercoiled plasmid DNA is susceptible to fluid stress in large‐scale manufacturing processes. A capillary device was used to generate controlled shear conditions and the effects of different stresses on plasmid DNA structure were investigated. Computational fluid dynamics (CFD) analysi