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DNA topoisomerase I and IIα expression in penile carcinomas: assessing potential tumour chemosensitivity

✍ Scribed by Daniel M. Berney; Elzbieta Stankiewicz; Ahmed M.A. Adlan; Sakunthala Kudahetti; Olaf J. Biedrzycki; Paul Hadway; Nick Watkin; Cathy Corbishley


Book ID
109054071
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
226 KB
Volume
102
Category
Article
ISSN
1464-4096

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## Abstract ## Background. Despite recent advances in the diagnosis and treatment of oral carcinoma, outcomes remain disappointing. The identification of new prognostic factors is necessary to improve survival. To determine the prognostic significance of cyclooxygenase (COX)‐2 and DNA topoisomeras