DNA stemline heterogeneity in colorectal cancer
✍ Scribed by Wolfgang Hiddemann; Dirk B. von Bassewitz; Hans-Jürgen Kleinemeier; Elisabeth Schulte-Brochterbeck; Jan Hauss; Berud Lingemann; Thomas Büchner; Ekkehard Grundmann
- Book ID
- 102672364
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 540 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0008-543X
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In vitro cultivated cells of 28 colorectal cancers were analyzed for chromosomal abnormalities that might signal amplification of DNA, either as double minutes (DMs) or homogeneously staining chromosomal regions (HSRs). Cells derived from 18 tumors showed DMs in I0 to IOO% of all metaphases examined