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DNA single- and double-strand breaks by alkaline- and immuno-comet assay in lymphocytes of workers exposed to styrene

✍ Scribed by Maria Enrica Fracasso; Denise Doria; Mariella Carrieri; Giovanni Battista Bartolucci; Sonia Quintavalle; Edoardo De Rosa


Book ID
119380779
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
325 KB
Volume
185
Category
Article
ISSN
0378-4274

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Determination of DNA single-strand break
✍ Einhaus, M. ;Holz, O. ;MeiοΏ½ner, R. ;Krause, T. ;Warncke, K. ;Held, I. ;Scherer, πŸ“‚ Article πŸ“… 1994 πŸ› Springer-Verlag 🌐 English βš– 636 KB

The detection of DNA single-strand breaks (SSB) in human mononucleated white blood cells (MWBC) using a modified version of the nick translation assay is presented. This assay allows rapid and sensitive examination of SSB using only 5 ml heparinized blood fo'~ an eightfold determination. The assay w