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DNA Sequence Detection Using Selective Fluorescence Quenching of Tagged Oligonucleotide Probes by Gold Nanoparticles

✍ Scribed by Li, Huixiang; Rothberg, Lewis J.


Book ID
115485953
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
132 KB
Volume
76
Category
Article
ISSN
0003-2700

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## Abstract The short sequence related to hepatitis C virus (HCV1) is detected by a label‐free DNA hybridization biosensor. The sensor relies on the immobilization of a 20‐mer oligonucleotide containing 2 guanine and 11 cytosine bases denoted PHCV1 as probe on the pencil graphite electrode (PGE). T