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DNA sequence analysis of mutations induced by melphalan in the CHO aprt locus

✍ Scribed by M.J. Finley Austin; Yi-Hong Han; Lawrence F. Povirk


Book ID
119105532
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
576 KB
Volume
64
Category
Article
ISSN
0165-4608

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## Abstract Gamma radiation–induced gene rearrangements at the Chinese hamster ovary cell locus coding for the purine salvage enzyme adenine phosphoribosyl transferase (APRT) consist of both simple deletions and more complex alterations that are presumably the result of multiple strand breaks. To c