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DNA replication and repair in ataxia telangiectasia cells exposed to bleomycin

✍ Scribed by Clive Morris; Rahmah Mohamed; Martin F. Lavin

Book ID: 116107933
Publisher: Elsevier Science
Year: 1983
Weight: 393 KB
Volume: 112
Category: Article
ISSN: 0167-8817
DOI: 10.1016/0167-8817(83)90011-1

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## Abstract Bleomycin, a radiomimetic glycopeptide, inhibits de novo DNA synthesis in ataxia telangiectasia lymphoblastoid B cells to a markedly lesser extent than in normal and xeroderma pigmentosum lymphoid cells. This observaton is similar to that following ionizing radiation; however, the effec