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Bleomycin induced inhibition of dna synthesis in ataxia-telangiectasia cell lines

โœ Scribed by M.J. Edwards; A.M.R. Taylor; E.J. Flude

Book ID
119407080
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
318 KB
Volume
102
Category
Article
ISSN
0006-291X

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The effect of bleomycin on DNA synthesis
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โœ Cohen, Maimon M. ;Simpson, Stacy J. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Wiley (John Wiley & Sons) โš– 567 KB

## Abstract Bleomycin, a radiomimetic glycopeptide, inhibits de novo DNA synthesis in ataxia telangiectasia lymphoblastoid B cells to a markedly lesser extent than in normal and xeroderma pigmentosum lymphoid cells. This observaton is similar to that following ionizing radiation; however, the effec