DNA replication and indirect induction of the SOS response in Escherichia coli
β Scribed by D'Ari, Richard; Huisman, Olivier
- Book ID
- 121779442
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 418 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0300-9084
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The striking similarity between the treatments that induce SOS functions and those that result in stable DNA replication (continuous DNA replication in the absence of protein synthesis) prompted us to examine the possibility of stable DNA replication being a recA+ lexA+-dependent SOS function. In ad
## Abstract The SOS system in __Escherichia coli__ is induced in response to DNA damage and the arrest of DNA synthesis. Here we show that in AB1157 bacteria starved for arginine, conditions for induction of adaptive mutations, the LexAβdependent SOS system is induced, but that this occurs only whe