β Scribed by Vengrova S. (Ed.)
No coin nor oath required. For personal study only.
InTech. 2011. 806 p.
Over the past decades, great advances have been made in understanding the cellular DNA repair pathways. At the same time, a wealth of descriptive knowledge of human diseases has been accumulated. Now, the basic research of the mechanisms of DNA repair is merging with clinical research, placing the action of the DNA repair pathways in the context of the whole organism. Such integrative approach enables understanding of the disease mechanisms and is invaluable in improving diagnostics and prevention, as well as designing better therapies. This book highlights the central role of DNA repair in human health and well-being. The reviews presented here, contain detailed descriptions of DNA repair pathways, as well as analysis of a large body of evidence addressing links between DNA damage repair and human health. They will be of interest to a broad audience, from molecular biologists working on DNA repair in any model system, to medical researchers.ContentsPrefaceDNA Repair MechanismsDNA Repair, Human Diseases and AgingΠΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½Ρ;ΠΠ΅Π½Π΅ΡΠΈΠΊΠ°;ΠΠ΅Π½Π΅ΡΠΈΠΊΠ° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°
π SIMILAR VOLUMES
<p><P>DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. </P></p>
<p>Physical and chemical agents in the environment damage the DNA of humans, and pose a major threat to human health today, and to the genetic integrity of human populations. Although studies on isolated DNA in vitro, on prokaryotes, on mammalian cells in culture, and on laboratory animals have prov
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
<p><span>DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. </span></p>
<p>In recent years it has become increasingly apparent that DNA repair processes play key roles in protecting genome integrity, where the failure of repair systems is directly responsible for many, if not the majority of, cancers. In DNA Damage and Repair, Vol. III: Advances from Phage to Humans, Ja