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DNA repair and colon cancer

✍ Scribed by Dorothy Bonn

Book ID
118553279
Publisher
The Lancet
Year
1993
Tongue
English
Weight
161 KB
Volume
342
Category
Article
ISSN
0140-6736

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Identification of DNA mismatch repair ge
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Hereditary nonpolyposis colorectal cancer (HNPCC) is a common autosomal dominant disease caused by germline mutations in DNA mismatch repair genes. The mutational spectrum in these genes appears to be diverse, in both the distribution and the nature of the mutations. However, most described mutation