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Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis

✍ Scribed by Susan J. Duthie


Publisher
Springer
Year
2010
Tongue
English
Weight
222 KB
Volume
34
Category
Article
ISSN
0141-8955

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In breast and colon adenocarcinomas methylation patterns at CCGG sites of several loci located on the short arm of chromosome 11 were determined by Southern blot analysis. Results obtained indicate that all tumor samples (20/20) exhibit DNA methylation changes when compared to their normal counterpa