𝔖 Bobbio Scriptorium
✦   LIBER   ✦

DNA Rearrangements in Human Follicular Lymphoma Can Involve the 5′or the 3′Region of the bcl-2 Gene

✍ Scribed by Yoshihide Tsujimoto, Muhammad M. Bashir, Iris Givol, Jeffrey Cossman, Elaine Jaffe and Carlo M. Croce


Book ID
123634036
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
619 KB
Volume
84
Category
Article
ISSN
0027-8424

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Structural Alterations in the 5′ Region
✍ Vasiliki Mikraki; Marc Ladanyi; Dr. R. S. K. Chaganti 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 698 KB

We report a new class of molecular lesions in the 5' region of the BCL2 protooncogene when it undergoes a t( 14; 18) translocation-associated rearrangement in the major break cluster (MBR) or minor break cluster (MCR) regions. Among 52 tumors assayed for BCL2 rearrangements using the MBR, MCR, and 5

Multiple DNA Rearrangements in the BCL2
✍ Erik Lundgren; Göran Roos; Ingrid Nordenson; Anders Wahlin; Jack Lind 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 572 KB

A 39-year-old male with follicular non-Hodgkin's lymphoma was repeatedly studied with respect to D N A rearrangements with the two probes pFL-I and pFL-2, representing two segments of chromosome 18. The oncogene BCL2, detected by pFL-I, was as expected translocated to the J region of the immunoglobu