We report a new class of molecular lesions in the 5' region of the BCL2 protooncogene when it undergoes a t( 14; 18) translocation-associated rearrangement in the major break cluster (MBR) or minor break cluster (MCR) regions. Among 52 tumors assayed for BCL2 rearrangements using the MBR, MCR, and 5
✦ LIBER ✦
DNA Rearrangements in Human Follicular Lymphoma Can Involve the 5′or the 3′Region of the bcl-2 Gene
✍ Scribed by Yoshihide Tsujimoto, Muhammad M. Bashir, Iris Givol, Jeffrey Cossman, Elaine Jaffe and Carlo M. Croce
- Book ID
- 123634036
- Publisher
- National Academy of Sciences
- Year
- 1987
- Tongue
- English
- Weight
- 619 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/29190
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