Current knowledge on the mechanisms of chemical carcinogenesis forms the basis for application of select short-term in vitro and in vivo tests to detect potential human carcinogens, for ultimate application to hazard assessment. Chemical carcinogenesis involves a series of distinct steps, proceeding
โฆ LIBER โฆ
DNA-Reactive Carcinogens: Mode of Action and Human Cancer Hazard
โ Scribed by Preston, R. Julian; Williams, Gary M.
- Book ID
- 111893657
- Publisher
- Informa plc
- Year
- 2005
- Tongue
- English
- Weight
- 167 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1040-8444
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The binding of native and reactive oxygen species-modified DNA (ROS-DNA) to circulating antibodies in the serum of patients with various types of cancer has been investigated by competition enzyme-linked immunosorbent assay. Fifteen sera of 35 showed reactivity with native and/or ROS-DNA. Eleven of