DNA-Protein Interactions. Principles and Protocols

✍ Scribed by G. Geoff Kneale

Publisher: Humana Press
Year: 1994
Tongue: English
Leaves: 424
Series: Methods in Molecular Biology
Edition: 1st
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

The clear and easy-to-follow protocols collected here illuminate the molecular basis of protein-nucleic acid interactions. Use them successfully to reveal the location of the DNA binding site, the strength and specificity of a binding, the identities of individual groups on the actual bases involved in binding, and the specific amino acid residues of the protein that interact with the DNA. Some of the techniques can even be used to identify previously unknown DNA binding proteins from crude cell extracts, thus empowering you to make groundbreaking advances in your work.

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