Dna ploidy status and DNA content instability within single tumors in renal cell carcinoma
โ Scribed by P. P. Bringuier; R. Bouvier; N. Berger; E. Piaton; J. P. Revillard; P. Perrin; M. Devonec
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 483 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Deoxyribonucleic acid (DNA) content was retrospectively determined by single-cell cytophotometry in primary tumors and corresponding metastases from 32 patients with renal cell carcinoma. In 15 of the primary tumors a diploid/near diploid and in 17 an aneuploid DNA content was found. A diploid/near
## BACKGROUND. A multiple sampling study was performed on 124 specimens of renal cell carcinomas to analyze the consistency and reliability of DNA measurements. The authors investigated intratumoral DNA heterogeneity and its role as a adverse prognostic factor for disease progression. ## METHODS
## BACKGROUND. Greater than 20% of patients with apparently localized renal cell carcinoma (RCC) present with disease progression after surgery. The objective of the current study was to improve the ability of clinicians to predict prognosis in patients with localized RCC. ## METHODS. The authors