๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

DNA Mismatch Repair: Functions and Mechanisms

โœ Scribed by Ravi R. Iyer; Anna Pluciennik; Vickers Burdett; Paul L. Modrich

Publisher
John Wiley and Sons
Year
2006
Weight
15 KB
Volume
37
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

๐Ÿ“œ SIMILAR VOLUMES

DNA mismatch repair and colorectal cance
DNA mismatch repair and colorectal cancer
โœ Toft, Neil J.; Arends, Mark J. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 148 KB ๐Ÿ‘ 2 views

Colorectal cancer is the second commonest malignancy in the western world, accounting for 20 000 deaths in the U.K. per year. Over the last 10 years, great strides have been made in our understanding of the molecular controls governing the transition from normal mucosa, through adenoma, and finally

Mechanisms underlying mismatch repair de
Mechanisms underlying mismatch repair deficiencies in normal cells
โœ Yuri K. Moliaka; Marina Cella; Alla P. Chudina; Tatiana N. Kolesnikova; Luigi Te ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 163 KB

Hereditary nonpolyposis colon cancer (HNPCC) is an autosomal dominantly inherited cancer predisposition which is linked to heterozygous mutations in mismatch repair genes. HNPCC tumour cells, in which the remaining wild-type copy of the mismatch repair gene is inactivated, display instability of mic

Structure and function of the components
Structure and function of the components of the human DNA mismatch repair system
โœ Thomas Jascur; C. Richard Boland ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 347 KB

## Abstract DNA mismatch repair (MMR) is one of the several enzyme systems involved in DNA homeostasis. DNA MMR is involved in the repair of specific types of errors that occur during new DNA synthesis; loss of this system leads to an accelerated accumulation of potential mutations, and predisposes

Cancer risk in mutation carriers of DNA-
Cancer risk in mutation carriers of DNA-mismatch-repair genes
โœ Markku Aarnio; Risto Sankila; Eero Pukkala; Reijo Salovaara; Lauri A. Aaltonen; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 46 KB ๐Ÿ‘ 2 views

Excessive incidence of various cancers is a challenging feature of the hereditary-non-polyposis-colorectal-cancer (HNPCC) syndrome. This study estimated the cancer incidences in HNPCC compared with the general population. Individuals in a cohort of 1763 members of 50 genetically diagnosed families w