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DNA methyltransferase Dnmt1 and mismatch repair

โœ Scribed by Wang, Keh-Yang; James Shen, C-K

Book ID
110069174
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
161 KB
Volume
23
Category
Article
ISSN
0950-9232

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โœ Jharna Datta; Kalpana Ghoshal; Sudarshana M. Sharma; Shoji Tajima; Samson T. Jac ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 355 KB

## Abstract De novo DNA methyltransferases, Dnmt3a and 3b, were purified by fractionation of Sโ€100 extract from mouse lymphosarcoma cells through several chromatographic matrices followed by glycerol density gradient centrifugation. Dnmt3a was separated from Dnmt3b and Dnmt1 in the first column, Qโ€