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DNA methylation with a sting: An active DNA methylation system in the honeybee

✍ Scribed by Matthias Schaefer; Frank Lyko

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
107 KB
Volume
29
Category
Article
ISSN
0265-9247

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✦ Synopsis

Abstract

The existence of DNA methylation in insects has been a controversial subject over a long period of time. The recently completed genome sequence of the honeybee Apis mellifera has revealed the first insect with a full complement of DNA methyltransferases.1 A parallel study demonstrated that these enzymes are catalytically active and that Apis genes can be methylated in specific patterns.2 These findings establish bees as a model to analyze the function of DNA methylation systems in invertebrate organisms and might also be important to understand evolutionary aspects of DNA methylation in higher eukaryotes. BioEssays 29: 208–211, 2007. Β© 2007 Wiley Periodicals, Inc.

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