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DNA methylation in prostate cancer

✍ Scribed by Long-Cheng Li; Steven T. Okino; Rajvir Dahiya

Book ID
113486576
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
321 KB
Volume
1704
Category
Article
ISSN
0304-419X

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Molecular biologic studies have now identified a number of important genetic and epigenetic mechanisms that cause alterations in growth and differentiation genes in prostate cancer. In addition to DNA deletion and point mutation, DNA methylation represents a new paradigm for the inactivation of tumo