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DNA methylation and epigenetic regulation in bone

✍ Scribed by S. Kato

Book ID: 116324181
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 52 KB
Volume: 48
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2011.03.028

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## Abstract During differentiation and development cells undergo dramatic morphological and functional changes without any change in the DNA sequence. The underlying changes of gene expression patterns are established and maintained by epigenetic processes. Early mechanistic insights came from the