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Redox regulation of the epigenetic landscape in cancer: DNA methylation and beyond

✍ Scribed by Rick Domann


Book ID
113632104
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
222 KB
Volume
51
Category
Article
ISSN
0891-5849

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## Abstract We recently identified germline methylation of __KILLIN__, a novel p53‐regulated tumor suppressor proximal to __PTEN__, in >1/3 Cowden or Cowden syndrome‐like (CS/CSL) individuals who are __PTEN__ mutation negative. Individuals with germline __KILLIN__ methylation had increased risks of