## Communicated by Stylianos E. Antonarakis fied by polymerase chain reaction (PCR) ace cording to Saiki et al. (1988) using the intronic primers of Lubahn et al. (1989). Routinely, 32 cycles were run in an Intelligent Heating Block (Biometra) after a first denaturation step for 5 min at 93ยฐC, 60
โฆ LIBER โฆ
DNA linkage analysis and studies of the androgen receptor gene in a large kindred with complete androgen insensitivity
โ Scribed by Imperato-McGinley, Julianne ;Ip, Nancy Y. ;Gautier, Teofilo ;Neuweiler, John ;Gruenspan, Harry ;Liao, Shutsung ;Chang, Chawnshang ;Balazs, Ivan
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 500 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0148-7299
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## Abstract Changes in the length of a polymorphic trinucleotide (CAG) repeat in the androgen receptor (AR) gene, which may lead to altered transactivation of the AR gene, have been implicated to play a role in the pathogenesis of several forms of endocrine cancer and certain reproductive disorders