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DNA ligase activity on chromatin and its analogs. Rejoining of DNA strands in polylysine-DNA complexes and in reconstituted chromatins

✍ Scribed by Zimmerman, Steven B.; Levin, Cora J.

Book ID
126101271
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
843 KB
Volume
14
Category
Article
ISSN
0006-2960

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## Abstract Using the technique of neutral elution through polycarbonate filters as a measure of DNA length, and hence of the number of double‐strand breaks incurred as a result of radiation damage, we found that normal human fibroblasts rejoin 50% of all breaks within only 3 min (37Β°C). This fast