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DNA Interstrand Cross-Link Formation Induced by Bioxalomycin α 2

✍ Scribed by Williams, Robert M.; Herberich, Brad


Book ID
127076674
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
107 KB
Volume
120
Category
Article
ISSN
0002-7863

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Methylglyoxal (MG) , a dietary mutagen, is present in various frequently consumed beverages and foods and in cigarette smoke. A combination of S, nuclease hydrolysis and alkaline unwinding assay was used to demonstrate the formation of single-strand breaks and interstrand cross-links in DNA upon tr