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DNA hypomethylation in breast cancer: An independent parameter of tumor progression?

✍ Scribed by J. Bernardino; C. Roux; A. Almeida; N. Vogt; A. Gibaud; M. Gerbault-Seureau; H. Magdelenat; C.A. Bourgeois; B. Malfoy; B. Dutrillaux

Book ID
114136187
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
596 KB
Volume
97
Category
Article
ISSN
0165-4608

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## BACKGROUND. The global DNA methylation of 136 breast lesions (117 primary invasive carcinomas, 5 benign phyllodes tumors, 11 fibroadenomas, and 3 sclerosing adenosis) and their respective adjacent parenchyma was analyzed using an in vitro enzyme assay. ## METHODS. In the group of patients wi