## Abstract DNA fragmentation was examined in situ in flashfrozen human postmortem midbrain as a marker for programmed cell death. A large series of cases comprising 16 pathologically confirmed idiopathic Parkinson's disease (IPD) cases, 14 control cases without brain pathology, and a group of 6 pa
DNA fragmentation in apoptosis
β Scribed by ZHANG, Jian Hua; XU, Ming
- Book ID
- 110020414
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 135 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0007-0610
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## Abstract In order to evaluate the reliability of fibroblasts as a cell model for studying apoptosis, we tested the response of normal human fibroblasts to the oxidative stress inducers H~2~O~2~ and 2βdeoxyβDβribose (dRib). Our results showed that fibroblasts treated with dRib and H~2~O~2~ are in