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DNA fragmentation assay — A useful tool or a red herring?

✍ Scribed by J.C.Y. Hu; D. Monahan; Q.V. Neri; Z. Rosenwaks; G.D. Palermo

Book ID
116479900
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
42 KB
Volume
96
Category
Article
ISSN
1556-5653

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## Abstract DNA degradation to oligonucleosome size fragments is one of the cellular markers of apoptosis. Based on DNA filter elution methodology, we have designed a simple assay to monitor apoptosis‐associated DNA fragmentation from cultured cells or from a reconstituted cell‐free system. The cel