𝔖 Bobbio Scriptorium
✦   LIBER   ✦

DNA damage-induced cell-cycle phase regulation of p53 and p21waf1 in normal and ATM-defective cells

✍ Scribed by Delia, Domenico; Fontanella, Enrico; Ferrario, Cristina; Chessa, Luciana; Mizutani, Shuki

Book ID
110068170
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
143 KB
Volume
22
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Abrogation of apoptosis induced by DNA-d
Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations
✍ Takashi Kawasaki; Yoshihiko Tomita; Vladimir Bilim; Masayuki Takeda; Kota Takaha πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 570 KB

The p53-inducible cyclin-dependent kinase inhibitor, p2 I / WAFI/CIPI (p2I), plays a pivotal role in the GI arrest or apoptosis of cells expored to genotoxic stimuli. To determine whether p2 I is a putative tumor-suppressor gene, p2 I status was investigated in 4 human bladder-cancer cell lines of k

Arecoline-induced phosphorylated p53 and
Arecoline-induced phosphorylated p53 and p21WAF1 protein expression is dependent on ATM/ATR and phosphatidylinositol-3-kinase in clone-9 cells
✍ Wen-Wen Chou; Jinn-Yuh Guh; Jung-Fa Tsai; Chi-Ching Hwang; Shean-Jaw Chiou; Lea- πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 368 KB

## Abstract Betel‐quid use is associated with liver cancer whereas its constituent arecoline is cytotoxic, genotoxic, and induces p53‐dependent p21^WAF1^ protein expression in Clone‐9 cells (rat hepatocytes). The ataxia telangiectasia mutated (ATM)/rad3‐related (ATR)‐p53‐p21^WAF1^ and the phosphati