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DNA damage and decreased DNA repair in individuals exposed to arsenic and lead in a mining site

✍ Scribed by I.N. Pérez-Maldonado; Y. Jasso-Pineda; F. Díaz-Barriga

Book ID
116923569
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
87 KB
Volume
196
Category
Article
ISSN
0378-4274

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## Abstract Arsenic is well established as a human carcinogen, but its precise mechanism of action remains unknown. Arsenic does not directly damage DNA, but may act as a carcinogen through inhibition of DNA repair mechanisms, leading indirectly to increased mutations from other DNA damaging agents