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DNA-binding products of nornitrogen mustard, a metabolite of cyclophosphamide

✍ Scribed by Kari Hemminki


Book ID
113136986
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
815 KB
Volume
61
Category
Article
ISSN
0009-2797

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Rat liver microsome-mediated binding of
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy