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DNA Analysis in the differential diagnosis of osteosarcoma

✍ Scribed by Henrik C. F. Bauer; Andris Kreicbergs; Claes Silfverswärd; Bernhard Tribukait


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
833 KB
Volume
61
Category
Article
ISSN
0008-543X

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Comparative genomic hybridization analysis of a primary osteosarcoma and its metastasis revealed two regions of DNA amplification, one at 17p11.2-12 and one at 19q12-13. Subsequent representational difference analysis of the primary tumor resulted in the isolation of two distinct tumor-amplified DNA