Both carcinogenic NF and AAF are metabolized to a common N-hydroxy metabolite, N-OH-AF. We investigated oxidative DNA damage by N-OH-AF, using (32)P-labeled human DNA fragments from the human p53 and p16 tumor-suppressor genes and the c-Ha-ras-1 protooncogene. N-OH-AF caused Cu(II)-mediated DNA dama
✦ LIBER ✦
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds
✍ Scribed by Gerhard Eisenbrand; Norbert Müller; Elvira Denkel; Walter Sterzel
- Book ID
- 112294089
- Publisher
- Springer-Verlag
- Year
- 1986
- Tongue
- English
- Weight
- 790 KB
- Volume
- 112
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Oxidative DNA damage by a common metabol
✍
Mariko Murata; Yumiko Yoshiki; Mariko Tada; Shosuke Kawanishi
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
French
⚖ 328 KB
Carcinogenic polycyclic aromatic hydroca
✍
William M. Baird; Louisa A. Hooven; Brinda Mahadevan
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 173 KB
👁 1 views
Influences of DNA isolation and RNA cont
✍
R.W.L. Godschalk; L.M. Maas; J.C.S. Kleinjans; F.J. Van Schooten
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 148 KB
👁 2 views
P-Postlabeling is a widely applied assay for the analysis of carcinogen-DNA adducts. Optimization of most steps in this assay has been given attention, but influences of DNA isolation and DNA purity on adduct quantitation have not been investigated systematically. In this study, DNA was isolated fro
Nucleoside and DNA Adducts from N-Nitros
✍
Loeppky, Richard N.; Shi, Jianzheng
📂
Article
📅
2008
🏛
American Chemical Society
🌐
English
⚖ 800 KB
MTHFR polymorphisms, folate intake and c
✍
Mi-Sun Lee; Kofi Asomaning; Li Su; John C. Wain; Eugene J. Mark; David C. Christ
📂
Article
📅
2012
🏛
John Wiley and Sons
🌐
French
⚖ 247 KB
DNA adducts as markers of exposure to ca
✍
Paolo Vineis; Frederica Perera
📂
Article
📅
2000
🏛
John Wiley and Sons
🌐
French
⚖ 42 KB
👁 2 views