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Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action

✍ Scribed by William M. Baird; Louisa A. Hooven; Brinda Mahadevan


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
173 KB
Volume
45
Category
Article
ISSN
0893-6692

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Markers of exposure to polycyclic aromatic hydrocarbons (urinary I -hydroxypyrene-glucuronide) and aromatic arnines (4-aminobiphenyl-hemoglobin adducts), as well as urinary mutagenicity, were measured in 47 healthy smokers and 50 nonsmokers. DNA adducts were determined by P32-postlabeling in the exf