The nuclease P1 modification of the 32 P-postlabeling DNA-adducts in the embryo cells, which suggests that technique was used to study the biological activity the enzymatic composition of the target tissue probaof 7H-dibenzo[c,g]carbazole (DBC) and some of its bly is the determining factor in the or
✦ LIBER ✦
DNA-adduct formation in primary mouse embryo cells induced by DBC and its organ-specific carcinogenic derivatives
✍ Scribed by A. Gabelova; O. Périn-Roussel; Y. Jounaidi; F. Périn
- Book ID
- 114133271
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 179 KB
- Volume
- 360
- Category
- Article
- ISSN
- 0165-1161
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## Abstract The cytochrome P4501A subfamily (CYP1A) is involved in the metabolic activation of __7H__‐dibenzo[__c,g__]carbazole (DBC) and its tissue‐ and organ‐specific derivatives, __N__‐methyldibenzo[__c,g__]carbazole (MeDBC)and 5,9‐dimethyldibenzo[__c,g__]carbazole (diMeDBC). In this study, we h