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DNA adduct formation by secondary metabolites of cyclopenta[cd]pyrene in vitro

✍ Scribed by Ching-Hung Hsu; Paul L. Skipper; Steven R. Tannenbaum


Book ID
117469297
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
193 KB
Volume
136
Category
Article
ISSN
0304-3835

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Metabolism of Benzo(a)pyrene by Human Ep
✍ Jack Bartley; James C. Bartholomew; Martha R. Stampfer πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 904 KB

## Abstract We demonstrate in cell culture that mammary epithelial cells from normal human breast specimens metabolize benzo(a)pyrene (BaP) and form adducts with the bases of their DNA more readily and at lower concentrations of BaP than do fibroblasts from the same specimens. BaP metabolism and ad