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DLC-1:a Rho GTPase-activating protein and tumour suppressor

✍ Scribed by Marian E. Durkin; Bao-Zhu Yuan; Xiaoling Zhou; Drazen B. Zimonjic; Douglas R. Lowy; Snorri S. Thorgeirsson; Nicholas C. Popescu

Book ID
114778287
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2007
Tongue
English
Weight
656 KB
Volume
11
Category
Article
ISSN
1582-1838

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## Abstract Mammalian MAP/ERK kinase kinase 1 (MEKK1) was identified as a mammalian homolog of Ste11p of the yeast pheromone‐induced mating pathway. Like Ste11p, MEKK1 is a MAP3 kinase linked to at least two MAP kinase cascades and regulatory events that require cytoskeletal reorganization. MEKK1 i