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Diversity of glutamate dehydrogenase in human brain

✍ Scribed by Gulnur Sh Burbaeva; Marina S Turishcheva; Elena A Vorobyeva; Olga K Savushkina; Elena B Tereshkina; Irina S Boksha

Book ID
117448915
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
324 KB
Volume
26
Category
Article
ISSN
0278-5846

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## Abstract Glutamate dehydrogenase (GDH) catalyzes the oxidative deamination of glutamate to α‐ketoglutarate using NAD or NADP as cofactors. In mammalian brain, GDH is located predominantly in astrocytes, where it is probably involved in the metabolism of transmitter glutamate. The exact mechanism