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Diversification of a Thieno[2,3- d ]pyrimidin-4-one Scaffold via Regioselective Alkylation Reactions

✍ Scribed by Dzhavakhishvili, Sergey G.; Gorobets, Nikolay Yu.; Shishkina, Svetlana V.; Shishkin, Oleg V.; Desenko, Sergey M.; Groth, Ulrich M.

Book ID: 120622805
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 474 KB
Volume: 11
Category: Article
ISSN: 1520-4766
DOI: 10.1021/cc9000373

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## Abstract The carbodiimides **4**, obtained from reactions of iminophosphorane **3** with aromatic isocyanates, were reacted with secondary amines to give 2‐dialkylamino‐5‐ethyl‐6‐methyl‐thieno[2,3‐__d__]pyrimidin‐4(3__H__)‐ones **6** in the presence of catalytic amount of EtONa. Reactions of **4

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